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OF GENETICS & CYTOLOGY

National Academy of Sciences of Belarus

The Reception: +375 17 378 18 56; E-mail: office@igc.by
Medical services: +375 33 380 50 40

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Genetic Testing for a Predisposition to Osteoporosis

Osteoporosis is a progressive bone disease that causes a decrease in bone density and the disruption of bone structure. With osteoporosis, the skeleton becomes weak, which leads to frequent fractures even in the case of minor injuries. The bones of the thoracic section and lumbar spine, wrists and hips are especially susceptible to fractures (so-called fragility fractures).

Osteoporosis risk groups:

  • Women over 65 years old;
  • Women suffering from oligoamenorrhea and infertility, as well as early surgical menopause in women under 50 years old;
  • Women after 3 or more pregnancies and childbirths;
  • People leading a sedentary lifestyle.

Osteoporosis is accompanied by the following symptoms:

  • Bone pain;
  • Frequent fractures;
  • Change in gait;
  • Poor posture;
  • Thinning skin, brittle nails, tooth loss;
  • Increased fatigue. Studies have shown that bone mineral density (BMD) is 60-85% dependent on the person’s genotype and the nature of this heredity is encoded in many genes.

DNA diagnostics makes it possible to identify a predisposition to osteoporosis.

Polymorphic gene variants analyzed:

VDR is associated with the metabolism of vitamin D in the body and its concentration in the blood serum. Vitamin D acts as an activator of many genes; its deficiency is associated with a decrease in BMD and the risk of bone fractures.

COL1A1, COL1A2 — the genes encoding collagen proteins, the organic component of bones. These proteins ensure the construction of the correct bone structure combining with the mineral component.

LCT is involved in the breakdown of milk sugar — lactose. Lactose intolerance is associated with a decrease in calcium absorption in the intestine, which can subsequently lead to a decrease in BMD. By taking a DNA test, you can find out about your individual characteristics for the timely preventive measures, the correction of your lifestyle and the prevention of decreased BMD.

Full test fee:

165,00 BYN

Please contact us to book an appointment:

 + 375 17 385 97 39 (landline); +375  33 380 50 40 (Viber, WhatsApp, Telegram)

We are waiting for you at the following address: 27 Akademicheskaya St., Room 119, Minsk

BOOKING AN APPOINTMENT ONLINE

27 Akademicheskaya St.
220072 Minsk
Belarus